Kiel Nano, Surface and Interface Science (KiNSIS)

High-throughput with particle technology for toxilogy and materials discovery (Prof. Mädler, IWT Bremen)

13.05.2019 ab 16:00

Technische Fakultät, Gebäude D, Kaisterstraße 2, Aquarium

Abstract

High-throughput screening is a well-established method for scientific experimentation in chemistry and biology. Examples are heterogeneous catalysts, drug developments and nanoparticle toxicology. These methods involve the synthesis of small sample volumes often in form of particles that are quickly tested. The tests are designed to quickly obtain easily accessible data (called descriptors) that are related with a predictor function to the desired properties. One particle based high-throughput concept for the evaluation of potential toxicological hazards will be introduced. Furthermore, a new concept called “Farbige Zustände” is presented which transfers high-throughput screening to the exploration of structural metals. The method comprises the synthesis of alloy samples in form of particles. The samples obtain a defined microstructure by fast or parallel thermal and mechanical treatments and are subsequently subjected to fast descriptor tests while a mathematical algorithm develops the predictor function.

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