Kiel Nano, Surface and Interface Science (KiNSIS)

Kolloquiumsvortrag: Dr. Carsten Wolters / Universität Münster

07.11.2014 von 14:45 bis 15:15

Institut für Informatik, Ludewig-Meyn-Str. 2, Übungsraum 2

Dr. Carsten Wolters

Modern numerical mathematics for source analysis from combined EEG and MEG data with applications in presurgical epilepsy diagnosis 



The accuracy of the inverse problem in Electro- (EEG) and Magnetoencephalography (MEG) source analysis strongly depends on the accuracy of the forward problem. For the forward problem, numerical approaches are needed to compute head surface field distributions from dipolar current sources in the human brain using realistic head volume conductor models derived from MRI sequences. For the forward problem, we will compare numerical and modeling accuracies of different procedures, under which are Lagrange and discontinuous Galerkin finite element methods, double-layer and symmetric boundary element methods. Both simplified multi-layer sphere models where quasi-analytical solutions exist as well as realistic head models will therefore be used. For the inverse problem, hierarchical Bayesian modeling and dipole scanning methods will be studied. We will then apply the developed methodology to a patient suffering from pharmaco-resistant focal epilepsy, where we will show that combined EEG/MEG source analysis using a calibrated realistic FE head model outperforms single modality EEG or MEG alone with regard to an improved non-invasive estimation of the seizure onset zone as well as an improved non-invasive reconstruction of the propagation pathway. Validation is carried out using additional depth electrode (sEEG) measurements.

Jane Eitzen, 0431 880-4461

Diesen Termin meinem iCal-Kalender hinzufügen






« Juli 2018 »
Mo Di Mi Do Fr Sa So
25 26
  • 16:15: Particle Physics after the Higgs Discovery: Where do we go? (Prof. Dr. Thomas Mannel, Siegen)
  • Klicken Sie, um Details zu allen 1 Terminen zu sehen.
27 28
  • 17:00: Bioinformatics tools for understanding the biological role of carbohydrates, Prof. Frederique Lisacek (Universität Genf)
  • Klicken Sie, um Details zu allen 1 Terminen zu sehen.
29 30 1
  • 17:15: tba, Leon Abelmann, "KIST Europe" und "University of Twente"
  • 19:00: Psychoaktive Pflanzen, Pilze und Tiere, Prof. Dr. Christian Peifer
  • Klicken Sie, um Details zu allen 2 Terminen zu sehen.
3 4 5 6 7 8
9 10
  • 17:00: To Catch a Thief, Dr. Giselher Herzer, Vacuumschmelze GmbH & Co. KG, Hanau
  • Klicken Sie, um Details zu allen 1 Terminen zu sehen.
11 12
  • 15:00: Nanopharmaceuticals - (nano)partikuläre Darreichungsformen für den Respirationstrakt?!, Prof. Dr. Regine Scherließ (Antrittsvorlesung)
  • Klicken Sie, um Details zu allen 1 Terminen zu sehen.
13 14 15
  • 17:15: Tba, Prof. Sawodny, Institut für Systemdynamik, Universität Stuttgart
  • Klicken Sie, um Details zu allen 1 Terminen zu sehen.
17 18 19 20 21 22
23 24 25 26 27 28 29
30 31 1 2 3 4 5