Kiel Nano, Surface and Interface Science (KiNSIS)

Termine & Veranstaltungen

Translational Breath Research for Clinical Diagnosis and Therapeutic Monitoring (Pablo Sinues, University of Basel)

21.01.2021 von 17:00 bis 18:00

Pablo SinuesProf. Pablo Sinues, University Children’s Hospital Basel (UKBB), Department of Biomedical Engineering, University of Basel, Switzerland

Exhaled breath is an under exploited body fluid, which contains valuable biochemical information at the metabolic level. Hence, it holds great potential as a non-invasive method to assist in clinical decision making. While there has been progress in making use of breath tests to guide clinical decision making, the full potential of exhaled breath analysis still remains to be exploited.
I will present a summary of the technical developments that allowed Secondary Electrospray Ionization-High Resolution Mass Spectrometry to become a reference analytical platform for real-time trace gas analysis. Bio-informatic tools developed in our lab unravel biochemical information encoded in the mass spectral fingerprints of our patients. Subsequently, I will illustrate how are we exploiting this technology in a clinical setting to address unmet clinical needs. For example, I will showcase how we use breath analysis to predict drug blood concentrations in epileptic patients, as well as risk estimates for drug therapy effects as well as side effects. Further examples of the potential of this technique include the diagnosis of infectious respiratory diseases, enabling the identification of the responsible pathogen within minutes. Ultimately, this work aims to improve diagnosis, to better phenotype complex pathophysiological processes, as well as to personalize therapy.

Link zum Zoom-Meeting
Das Kolloquium findet im Rahmen des GRK 2154 "Materials for Brain" statt, Interessierte sind herzlich eingeladen.

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Antrittsvorlesung: Theory and simulation of strongly correlated plasmas and dense matter (Dr. Hanno Kählert, ITAP, CAU)

26.01.2021 von 16:15 bis 17:45


High density plasmas are fundamentally different from their low density counterparts in space or high temperature fusion reactors. Strong interactions give rise to novel phenomena such as liquid-like ordering and affect their thermodynamic and transport properties. The latter are important for the modeling of dense plasmas in inertial confinement fusion or warm dense matter in planetary interiors. Similar conditions occur at low temperatures or when highly charged ions are involved, which makes it possible to study strong coupling physics on a smaller scale with laser-cooled plasmas or charged dust particles. This talk gives an introduction to the physics of strongly correlated plasmas, their occurrence, and theoretical description. In particular, simulation methods have become indispensable tools to obtain reliable data for their properties in a regime where traditional plasma theory fails. As an example, I present results for the dynamic structure factor - a key quantity that is accessible experimentally and provides deep insight into the thermodynamic, transport, and dielectric properties of strongly correlated plasmas. Future challenges and possible directions for the field will be addressed.

Zugang zum Zoom-Meeting
Part of the "Physikalisches Kolloquium", everybody is cordially invited.

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RV: Leicht und smart dank Funktion und Struktur / Materialien nur aus Luft

11.02.2021 von 18:00 bis 19:30


Doppelvortrag am 11. Februar:

  • Leicht und smart dank Funktion und Struktur
    M. Sc. Leonard Siebert, Universität Kiel

  • Materialien nur aus Luft
    Dr. Ing. Fabian Schütt, Universität Kiel


Der Vortrag ist Teil der Vorlesungsreihe „Nanotechnologie für den Unterricht“ – eine digitale Fortbildungsreihe zur Nanotechnologie als Thema für den Chemieunterricht. In den Sommerferien bietet die CAU in Kooperation mit KiNSIS, der Kieler Forschungswerkstatt und dem IQSH mit der „Nano-Summerschool“ regelmäßig eine mehrtägige Fortbildungsveranstaltung für Lehrkräfte an. Coronabedingt soll in diesem Jahr eine digitale Ringvorlesung interessierten Lehrkräften und Lehramtsstudierenden einen ersten Einblick in die Möglichkeiten der Nanotechnologie für den Chemieunterricht ermöglichen. In Vorträgen und Demoexperimenten werden dazu aktuelle Forschungsthemen und Anwendungen thematisiert und Anknüpfungspunkte für die Umsetzung im Unterricht aufgezeigt. Eine Vertiefung der Inhalte ist bei der Nano-Summerschool 2021 möglich.

Weitere Termine

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Surface Modification for Biomedicine via the Vapor Deposition of Polymers (Karen Gleason, MIT)

18.02.2021 von 17:00 bis 18:00

PKaren Gleasonrof. Karen Gleason, Massachusetts Institute of Technology (MIT), Department of Chemical Engineering, Cambridge, Massachusetts, USA

Multiple vapor deposited polymer compositions been demonstrated for biomedical applications including the surface modification of implants, biosensing, and tissue culture. Homopolymer and copolymer surfaces can be designed directly from the library of functional groups processed by the vapor phase monomers.  Post-deposition modification of the functional groups of the monomeric units in the polymer films with bioactive molecules further enhances the precise chemical signaling at the surface. For interactions with living cells and tissues, surface modification layers must be free of impurities and stable under the conditions of use. A vapor deposition approach eliminates the possibility of contamination by residual solvent. Additionally, purifying monomers, which are small molecules, is much easier than purifying macromolecular polymer chains. The method of initiated Chemical Vapor Deposition (iCVD) has produced uniform coverage over neural probes and lead wires. These implants have microscale geometric features which must be conformally encapsulated by high-purity, pinhole-free, electrically insulating polymer layers. These biopassivation layers must be thin in order to minimize the disruption caused by implantation into the cortex. Since film growth proceeds upwards from the substrate, iCVD offers the opportunity for interfacial engineering prior to beginning iCVD synthesis. Grafting is essential for tethering swellable hydrophilic surface modification layers. Indeed the durability of iCVD hydrogels and zwitterionic layers is greatly enhanced by grafting for the prevention of delamination.

Link zum Zoom-Meeting
Das Kolloquium findet im Rahmen des GRK 2154 "Materials for Brain" statt, Interessierte sind herzlich eingeladen.

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Benchside to Bedside: Imaging agents for cancer diagnosis (Dr. Garima Singh, ROTOP Pharmaka GmbH)

18.03.2021 von 17:00 bis 18:00


Garima Singh (R&D Project Manager, ROTOP Pharmaka GmbH, Dresden)

Abstract: tba

Link zum Zoom-Meeting
Das Kolloquium findet im Rahmen des GRK 2154 "Materials for Brain" statt, Interessierte sind herzlich eingeladen.

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